| 38 | 15:00 Sunday - 25 May | Tottenham Hotspur TOT | - |  Brighton & Hove AlbionBHA | Tottenham Hotspur Stadium | Planned |
| 37 | 19:00 Monday - 19 May | Brighton & Hove Albion BHA | - |  LiverpoolLIV | American Express Stadium | Planned |
| 36 | 14:00 Saturday - 10 May | Wolverhampton Wanderers WOL | - | Brighton & Hove AlbionBHA | Molineux Stadium | Planned |
| 35 | 13:00 Sunday - 4 May | Brighton & Hove Albion BHA | - |  Newcastle UnitedNEW | American Express Stadium | Planned |
| 34 | 14:00 Saturday - 26 April | Brighton & Hove Albion BHA7.2 | 3 - 2 | 6.8 West Ham UnitedWHU | American Express Stadium | Fulltime |
| 33 | 14:00 Saturday - 19 April | Brentford BRE 7.1 | 4 - 2 | 6.4 Brighton & Hove AlbionBHA | Gtech Community Stadium | Fulltime |
| 32 | 14:00 Saturday - 12 April | Brighton & Hove Albion BHA6.9 | 2 - 2 | 6.6 Leicester CityLEI | American Express Stadium | Fulltime |
| 31 | 14:00 Saturday - 5 April | Crystal Palace CRY 6.8 | 2 - 1 | 6.5 Brighton & Hove AlbionBHA | Selhurst Park | Fulltime |
| 30 | 18:45 Wednesday - 2 April | Brighton & Hove Albion BHA6.2 | 0 - 3 | 7.2 Aston VillaAVL | American Express Stadium | Fulltime |
| 29 | 15:00 Saturday - 15 March | Manchester City MCI 6.9 | 2 - 2 | 6.5 Brighton & Hove AlbionBHA | Etihad Stadium | Fulltime |
| 28 | 15:00 Saturday - 8 March | Brighton & Hove Albion BHA6.9 | 2 - 1 | 6.5 FulhamFUL | American Express Stadium | Fulltime |
| 27 | 19:30 Tuesday - 25 February | Brighton & Hove Albion BHA6.9 | 2 - 1 | 6.6 AFC BournemouthBOU | American Express Stadium | Fulltime |
| 26 | 15:00 Saturday - 22 February | Southampton SOU 6.1 | 0 - 4 | 7.5 Brighton & Hove AlbionBHA | St. Mary's Stadium | Fulltime |
| 25 | 20:00 Friday - 14 February | Brighton & Hove Albion BHA7.2 | 3 - 0 | 6.2 ChelseaCHE | American Express Stadium | Fulltime |
| 24 | 12:30 Saturday - 1 February | Nottingham Forest NFO 7.9 | 7 - 0 | 5.6 Brighton & Hove AlbionBHA | The City Ground | Fulltime |
| 23 | 15:00 Saturday - 25 January | Brighton & Hove Albion BHA6.4 | 0 - 1 | 7.0 EvertonEVE | American Express Stadium | Fulltime |
| 22 | 14:00 Sunday - 19 January | Manchester United MUN 6.2 | 1 - 3 | 7.0 Brighton & Hove AlbionBHA | Old Trafford | Fulltime |
| 21 | 19:30 Thursday - 16 January | Ipswich Town IPS 6.0 | 0 - 2 | 7.2 Brighton & Hove AlbionBHA | Portman Road | Fulltime |
| 20 | 17:30 Saturday - 4 January | Brighton & Hove Albion BHA6.6 | 1 - 1 | 6.6 ArsenalARS | American Express Stadium | Fulltime |
| 19 | 19:45 Monday - 30 December | Aston Villa AVL6.9 | 2 - 2 | 6.7 Brighton & Hove AlbionBHA | Villa Park | Fulltime |
| 18 | 19:30 Friday - 27 December | Brighton & Hove Albion BHA6.9 | 0 - 0 | 6.8 BrentfordBRE | American Express Stadium | Fulltime |
| 17 | 15:00 Saturday - 21 December | West Ham United WHU6.6 | 1 - 1 | 6.8 Brighton & Hove AlbionBHA | London Stadium | Fulltime |
| 16 | 14:00 Sunday - 15 December | Brighton & Hove Albion BHA6.4 | 1 - 3 | 7.0 Crystal PalaceCRY | American Express Stadium | Fulltime |
| 15 | 14:00 Sunday - 8 December | Leicester City LEI6.6 | 2 - 2 | 6.7 Brighton & Hove AlbionBHA | King Power Stadium | Fulltime |
| 14 | 19:30 Thursday - 5 December | Fulham FUL6.8 | 3 - 1 | 6.2 Brighton & Hove AlbionBHA | Craven Cottage | Fulltime |
| 13 | 20:00 Friday - 29 November | Brighton & Hove Albion BHA6.7 | 1 - 1 | 6.6 SouthamptonSOU | American Express Stadium | Fulltime |
| 12 | 15:00 Saturday - 23 November | AFC Bournemouth BOU6.5 | 1 - 2 | 7.0 Brighton & Hove AlbionBHA | Vitality Stadium | Fulltime |
| 11 | 17:30 Saturday - 9 November | Brighton & Hove Albion BHA6.8 | 2 - 1 | 6.6 Manchester CityMCI | American Express Stadium | Fulltime |
| 10 | 15:00 Saturday - 2 November | Liverpool LIV7.0 | 2 - 1 | 6.5 Brighton & Hove AlbionBHA | Anfield | Fulltime |
| 9 | 14:00 Saturday - 26 October | Brighton & Hove Albion BHA6.8 | 2 - 2 | 6.7 Wolverhampton WanderersWOL | American Express Stadium | Fulltime |
| 8 | 14:00 Saturday - 19 October | Newcastle United NEW6.5 | 0 - 1 | 7.1 Brighton & Hove AlbionBHA | St. James' Park | Fulltime |
| 7 | 15:30 Sunday - 6 October | Brighton & Hove Albion BHA6.8 | 3 - 2 | 6.6 Tottenham HotspurTOT | American Express Stadium | Fulltime |
| 6 | 14:00 Saturday - 28 September | Chelsea CHE7.1 | 4 - 2 | 6.3 Brighton & Hove AlbionBHA | Stamford Bridge | Fulltime |
| 5 | 13:00 Sunday - 22 September | Brighton & Hove Albion BHA6.8 | 2 - 2 | 6.6 Nottingham ForestNFO | American Express Stadium | Fulltime |
| 4 | 14:00 Saturday - 14 September | Brighton & Hove Albion BHA6.8 | 0 - 0 | 6.6 Ipswich TownIPS | American Express Stadium | Fulltime |
| 3 | 11:30 Saturday - 31 August | Arsenal ARS6.7 | 1 - 1 | 6.7 Brighton & Hove AlbionBHA | Emirates Stadium | Fulltime |
| 2 | 11:30 Saturday - 24 August | Brighton & Hove Albion BHA7.0 | 2 - 1 | 6.5 Manchester UnitedMUN | American Express Stadium | Fulltime |
| 1 | 14:00 Saturday - 17 August | Everton EVE6.1 | 0 - 3 | 7.2 Brighton & Hove AlbionBHA | Goodison Park | Fulltime |